Our Genetic Predisposition DNA Test will establish your genetic risk to 35 different diseases including some of the most common cancers and old age diseases. This test will help you determine whether you carry certain mutations in your DNA which are known to be related to specific hereditary illnesses. The results will establish the probability of developing the disease over the course of your life by reporting whether your predisposition to each disease is above or below the average risk of the general population. The price of the test starts at €209 and is for testing 1 person. Results are emailed in 4-5 weeks from receipt of samples.

Genetic Health tests are the latest development in DNA testing helping people to discover more about their health at a genetic level. Genetic predisposition DNA testing (or genetic health testing) enables you to take better control of your life and health. By knowing which diseases you stand a greater than average chance of developing, you can make changes to your lifestyle and diet to lessen the chances of developing the illness.  This DNA test might be even more useful if you have a history of a certain condition in the family. Perhaps the result might, much to your relief, tell you that you do not carry the disease-causing mutation for the hereditary illness and can therefore put your mind at rest.

Prevention is better than cure and when it comes to many illnesses, the most effective treatment is that which is administered when the disease is in its earliest stages. Knowing you are at risk of a disease means having regular checkups and following the right plan to reduce your risk.

The Genetic Predisposition DNA Test includes a total of 35 diseases in the following 5 categories. The test report you will receive includes all 35 diseases and conditions, they are not available individually except for the Coeliac Disease Test and Lactose Intolerance DNA Test.

Autoimmune Diseases

• Psoriasis
• Rheumatoid Arthritis
• Systemic Lupus Erythematosus (Lupus)

Eye Diseases

• Exfoliation Glaucoma
• Primary Open Angle Glaucoma

Cardiovascular Diseases

• Atrial Fibrillation
• Coronary Artery Disease (Heart Disease)
• Intracranial Aneurysm
• Peripheral Arterial Disease
• Venous Thromboembolism

Endocrine, Nutritional and Metabolic Diseases

• Coeliac Disease (Please click here to read about our separate Coeliac Disease DNA Test and see below for details about our Coeliac Disease upgrade)
• Folate Metabolism
• Gallstone Disease
• Graves’ Disease
• Higher Sugar Consumption
• Lactose Intolerance (Please click here to read about our separate Lactose Intolerance DNA Test and see below for details about our Lactose Intolerance upgrade)
• Obesity
• Type 1 Diabetes
• Type 2 Diabetes
• Vitamin B6 Metabolism
• Vitamin B12 Metabolism
• Vitamin D Metabolism

Neurological Diseases

• Alzheimer’s Disease
• Migraine with Aura
• Multiple Sclerosis

Oncological Diseases (Cancers)

• Basal Cell Carcinoma
• Bladder Cancer
• Breast Cancer
• Colorectal Cancer
• Gastric Cancer
• Lung Cancer
• Melanoma (Skin Cancer)
• Prostate Cancer

Other Conditions

• Male Pattern Baldness
• Osteoporosis

Click here to view a Sample Genetic Predisposition Results Report:

This genetic health DNA test is based on the analysis of 139 SNPs (Single Nucleotide Polymorphisms) including the most relevant SNPs for each condition. These are genetic variations occurring between individuals with each SNP representing a unit or building block which we call a “nucleotide”. These SNPs can alter the way a gene functions and affect protein synthesis. Some SNPs are known to increase a person’s risk of getting a particular disease. Scientists have studied many of the genetic variations that are associated with certain diseases and can today confirm whether an individual carries these variations through a genetic DNA test.

First and foremost, to be able to develop a sensible and effective plan of action following the results of this test you will need to work together with a doctor, genetic counsellor or a qualified nutritionist. Only somebody qualified can really help you understand the implications of the results and what changes are best made to your lifestyle, diet, exercise routine etc. They can also help you understand more about any family risks and hereditary issues as well as providing support and advice. Further to this, it is important to note that people with a high predisposition to a disease do not necessarily develop the illness. The NHS provides information about genetic counselling. It is important to note that in addition to your genes, external environmental factors as well as lifestyle and diet all play a role in whether a disease develops or not.

Samples for a genetic predisposition DNA test are collected using a simple home DNA sample collection kit. DNA required for the test is collected using sterile mouth swabs provided inside the kit. Step-by-step instructions and consent forms are also included.

You can view sample collection instructions on our How to Collect DNA Samples page.

Our Genetic Predisposition test examines a limited number of genes (40 SNPs, 26 genes and additional intergenic SNPs) associated with breast cancer and will report whether your genetic risk is above or below average. Our test is NOT a full gene screen and should not be interpreted as a clinical result. If you require a clinical result confirming whether or not you carry the gene variant known to greatly increase the chance of developing breast cancer then you should order a full BRCA 1 and BRCA 2 test.

For only an additional €45 you can add an advanced Coeliac Disease report to your Genetic Predisposition results. The full Coeliac Disease test will confirm or exclude the possibility of coeliac disease by testing 6 DNA markers for the HLA DQ2 and DQ8 genes and can rule out having coeliac disease with more than 99% accuracy. Click here to read more about our Coeliac Disease Test.

For only an additional €45 you can add an advanced Lactose Intolerance report to your Genetic Predisposition results. The full Lactose Intolerance test analyses the LCT gene and will report whether you are low or high risk. Click here to read more about our Lactose Intolerance DNA Test.

Please read our Health and Clinical Testing Terms and Conditions carefully and make sure you understand them before placing an order.

Please Contact Us with any questions you might have, to discuss your requirements or to place an order.

Disclaimer: Your test results are solely for informational and/or educational purposes only and should NOT be used for making medical, health or any other decisions without consulting a medical professional. Always speak to your doctor and seek professional help before taking action. The test does not replace a visit to a doctor, nor the advice or services of a doctor or other qualified specialist.

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